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李法辉

发布者:yxy    发布时间:2020-04-28

一、基本情况介绍

李法辉,男,博士,副教授,主要从事药物化学方面的研究。主持参与了多项国家自然科学基金、山东省医药科技发展项目等。获得省部级、市级奖励3项,发表SCI论文二十余篇,申请发明专利多项。

二、教学工作

承担本科《药物化学》及《药物合成反应》教学工作。

三、科研工作

1、代表性论著

[1] Guo Tiantian, Song Yiming, Lu Yinghui, Li Guolin, Liu Tian, Han Wenrong, Song Weiguo; Yang Chuncheng; Li Fahui*; Liu Qingchao*; Total synthesis and anticancer activity of  the natural oleanolic acid bidesmoside saponin, albidoside A, isolated from the roots of Acacia albida, Journal of Chemical Reasearch, 2020, 44(1-2): 42-49.

[2] Song Yiming, Guo Tiantian, Liu Qingchao*, Song Weiguo, Li Fahui*. A sequential one-pot strategy for the  synthesis of triterpenoid saponins in  ionic liquid [emim][OTf], Journal of Chemical Reasearch, 2019, 43(1-2): 20-25.

[3]  Li Kaoxue* Liu Chuanchao Wang Kang Ren Yang Li Fahui*.   Sodium borohydride-nickel chloride hexahydrate in EtOH/PEG-400 as an efficient and recyclable catalytic system for the reduction of alkenes, RSC advances,  2018, 8(14): 7761-7764.

[4] Li Kaoxue*, Wang Kang, Liu Chuanchao, Yang Xuhao, Chen Xia, Ren Yang, Fahuh Li*. Efficient and selective reduction of α-pinene to cis-pinane by NaBH4 using NiCl2•6H2O/PEG-800/ethanol as the catalytic system, Synthetic Communications, 2019, 49(5): 672-678.

[5] Cao Shuhua*, Fan Jiangli, Sun Wen, Li Fahui, Li Kaoxue, Tai Xishi, Peng Xiaojun. A Novel Mn-Cu Bimetallic Complex for Enhanced Chemodynamic Therapy with Simultaneous Glutathione Depletion, ChemComm, 2019, 55 12956-12959.